anti-G-CSF Receptor antibody [LMM741] (PE)

产品描述: PE-conjugated Mouse Monoclonal antibody [LMM741] recognizes G-CSF Receptor
反应物种: Hu
不反应物种: Ms
应用: FACS
特异性: The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.
宿主: Mouse
克隆: Monoclonal
克隆号: LMM741
同位型: IgG1, kappa

CAT.NO. : ARG42287

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Size:

50 tests

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Product Details

概述

产品描述	PE-conjugated Mouse Monoclonal antibody [LMM741] recognizes G-CSF Receptor
反应物种	Hu
不反应物种	Ms
应用	FACS
特异性	The mouse monoclonal antibody LMM741 recognizes an extracellular epitope of CD114 (colony stimulating factor 3 receptor), a 130 kDa transmembrane glycoprotein expressed on granulocytes and their differentiation stages, on monocytes, platelets, endothelial cells and placenta. It is absent from lymphocytes and erythrocytes.
宿主	Mouse
克隆	Monoclonal
克隆号	LMM741
同位型	IgG1, kappa
靶点名称	G-CSF Receptor
抗原物种	Human
抗原	CHO cells transfected with Human CD114.
偶联标记	PE
別名	G-CSF receptor; CD114; CD antigen CD114; G-CSF-R; GCSFR; Granulocyte colony-stimulating factor receptor

应用说明

应用建议

应用	推荐稀释比
FACS	10 µl / 100 µl of whole blood or 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified
缓冲液	PBS and 15 mM Sodium azide.
抗菌剂	15 mM Sodium azide
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1441 Human CSF3R Swiss-port # Q99062 Human Granulocyte colony-stimulating factor receptor
基因名称	CSF3R
全名	colony stimulating factor 3 receptor (granulocyte)
背景介绍	The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]
生物功能	Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. [UniProt]
细胞定位	Isoform 2: Secreted. Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	92 kDa
翻译后修饰	N-glycosylated. [UniProt]

检测图片 (1)

ARG42287 anti-G-CSF Receptor antibody [LMM741] (PE) FACS image
Flow Cytometry: Human peripheral blood stained with ARG42287 anti-G-CSF Receptor antibody [LMM741] (PE).

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