anti-IL18 antibody
Key features and details
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- 反应物种:
- 应用:
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- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG55332
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IL18 |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL18 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 37-193 of Human IL18 (NP_001553.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Iboctadekin; Interferon gamma-inducing factor; Interleukin-18; IL-18; IFN-gamma-inducing factor; IL-1 gamma; IGIF; IL-1g; Interleukin-1 gamma; IL1F4 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: PMID: 34603042 detected IL18 in paraffin-embedded ventricular tissues sections by this antibody. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL18 |
| 全名 | interleukin 18 |
| 背景介绍 | The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011] |
| 生物功能 | Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. [UniProt] |
| 研究领域 | Cancer antibody; Immune System antibody; Metabolism antibody |
| 预测分子量 | 22 kDa |
| 翻译后修饰 | The pro-IL-18 precursor is processed by CASP1 or CASP4 to yield the active form. |
检测图片 (2)
ARG55332 anti-IL18 antibody WB image
Western blot: HeLa cell lysate stained with ARG55332 anti-IL18 antibody.
ARG55332 anti-IL18 antibody IP image
Immunoprecipitation: 200 µg extracts of HeLa immunoprecipitated and stained with ARG55332 anti-IL18 antibody.
参考文献
Ginsenoside Rb1 alleviated concanavalin A-induced hepatocyte pyroptosis by activating mitophagy
WB / Human, Mouse
Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway
IHC-P / Mouse
Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein.
FACS / Mouse
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