anti-AK2 antibody [7E7]

CAT.NO. : ARG57157

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [7E7] recognizes AK2
反应物种	Hu
应用	ICC/IF, WB
宿主	Mouse
克隆	Monoclonal
克隆号	7E7
同位型	IgG1, kappa
靶点名称	AK2
抗原物种	Human
抗原	Recombinant fragment around aa. 1-239 of Human AK2
偶联标记	Un-conjugated
別名	ADK2; Adenylate kinase 2, mitochondrial; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; Adenylate monophosphate kinase; EC 2.7.4.3; AK 2

应用说明

应用建议

应用	推荐稀释比
ICC/IF	Assay-dependent
WB	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 204 Human AK2 Swiss-port # P54819 Human Adenylate kinase 2, mitochondrial
基因名称	AK2
全名	adenylate kinase 2
背景介绍	Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010]
生物功能	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. [UniProt]
预测分子量	26 kDa

检测图片 (3)

ARG57157 anti-AK2 antibody [7E7] ICC/IF image
Immunofluorescence: HeLa cells line stained with ARG57157 anti-AK2 antibody [7E7] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
ARG57157 anti-AK2 antibody [7E7] WB image
Western blot: 40 µg of 1) Kidney, and 2) Liver tissue lysates stained with ARG57157 anti-AK2 antibody [7E7] at 1:1000.
ARG57157 anti-AK2 antibody [7E7] WB image
Western blot: 40 µg of 1) HepG2, and 2) NIH/3T3 cell lysates stained with ARG57157 anti-AK2 antibody [7E7] at 1:1000.

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