anti-Cathepsin S antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Cathepsin S
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Cathepsin S
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human Cathepsin S.
  • Brand:
CAT.NO. : ARG40174
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Cathepsin S
反应物种Hu
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Cathepsin S
抗原物种Human
抗原Synthetic peptide derived from Human Cathepsin S.
偶联标记Un-conjugated
別名Cathepsin S; EC 3.4.22.27
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照U-87MG
实际分子量25 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1520 Human CTSS

Swiss-port # P25774 Human Cathepsin S

基因名称CTSS
全名cathepsin S
背景介绍The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
生物功能Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. [UniProt]
细胞定位Lysosome. [UniProt]
预测分子量37 kDa
检测图片 (1)
  • ARG40174 anti-Cathepsin S antibody WB image

    Western blot: U-87MG cell lysate stained with ARG40174 anti-Cathepsin S antibody.

参考文献

Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease

WB / Human

Yuan Cheng et al.
Acta Neuropathol.,  (2023)

publication_link

 

hr_line

Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer's disease.

WB / Human

Si-Han Chen et al.
Transl Psychiatry.,  (2020)

publication_link

 

hr_line
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