anti-Dengue virus NS1 antibody [SQab1502]

Key features and details

产品描述: Mouse Monoclonal antibody [SQab1502] recognizes Dengue virus NS1
反应物种: DEN
应用: ELISA, WB
特异性: This antibody recognizes DENV2 NS1 protein.
宿主: Mouse
克隆: Monoclonal
克隆号: SQab1502
同位型: IgG
靶点名称: Dengue virus NS1

Brand:

CAT.NO. : ARG65661

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Size:

100 μg

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*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [SQab1502] recognizes Dengue virus NS1
反应物种	DEN
应用	ELISA, WB
特异性	This antibody recognizes DENV2 NS1 protein.
宿主	Mouse
克隆	Monoclonal
克隆号	SQab1502
同位型	IgG
靶点名称	Dengue virus NS1
抗原物种	Virus
抗原	Recombinant hexamer Dengue virus NS1 protein from drosophila cell
偶联标记	Un-conjugated
別名	Dengue virus NS1 antibody; Dengue virus nonstructural glycoprotein NS1 antibody

应用说明

应用建议

应用	推荐稀释比
ELISA	1:1000 - 1:5000
WB	Assay-dependent

应用说明

Recommend using ARG65660 Dengue virus NS1 antibody [SQab1501] for WB, ICC/IF studies.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	PBS (pH 7.4) and 0.01% Thimerosal.
抗菌剂	0.01% Thimerosal
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称	DENV_gp1
全名	Dengue virus nonstructural protein 1
背景介绍	Dengue virus NS1 protein is a nonstructural protein which could be secreted and have been developed as diagnostic biomarker for early detection. There are several forms of NS1 including monomer, dimer, and hexamer during infection. Dimeric NS1 can be anchored to cell membranes with glycosyl-phosphatidylinositol (GPI). Hexameric NS1 can be secreted and detected in patients' blood samples (up to 50 μg/mL) or infected cell supernatants (various from ng/mL to μg/mL depend on serotypes and strains). Studies have shown that NS1 could interfere complement activity and prothrombin activation. In addition, NS1 could elicit antibodies which cross-react with host antigens including coagulation factors and molecules expressed in endothelial cells and platelets through molecular mimic.
生物功能	Dengue virus (DENV) non-structural protein 1 (NS1) is involved in virus replication and regulation of the innate immune response. Soluble and membrane-associated NS1 may activate human complement and induce host vascular leakage. This effect might explain the clinical manifestations of dengue hemorrhagic fever and dengue shock syndrome. [Uniprot]
产品亮点	Related Antibody Duos and Panels: ARG30252 Dengue virus NS1 ELISA Antibody Duo Related products: Dengue virus antibodies; Dengue virus ELISA Kits; Dengue virus Duos / Panels; Anti-Mouse IgG secondary antibodies; Related news: Best NS1 antibodies in the market Fighting fire with fire: Genetically-engineered mosquitoes as an alternative to fight diseases Tools for studying Dengue Virus Exploring Antiviral Immune Response
研究领域	Microbiology and Infectious Disease antibody

检测图片 (1)

ARG65661 anti-Dengue virus NS1 antibody [SQab1502] & ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) ELISA image
ELISA: 293 cells expressed dengue virus type 2 NS1 protein (major in hexamer) detected by ARG65661 anti-Dengue virus NS1 antibody [SQab1502] as capture antibody (2.5 μg/ml), and ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) (0.5 μg/ml) as detection antibody, followed by incubation with streptavidin-HRP.

参考文献

esigning Quantum Capacitive Peptide Interfaces for Electroanalytical Applications

ELISA / Dengue virus

Sarah T. R. Brandão et al.
Analytical Chemistry, (2023)