anti-eIF4E2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG56163
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes eIF4E2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | eIF4E2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human eIF4E2. |
| 偶联标记 | Un-conjugated |
| 別名 | Eukaryotic translation initiation factor 4E homologous protein; mRNA cap-binding protein type 3; EIF4EL3; IF4e; Eukaryotic translation initiation factor 4E type 2; 4E-LP; eIF4E-like protein 4E-LP; eIF-4E type 2; mRNA cap-binding protein 4EHP; eIF4E type 2; Eukaryotic translation initiation factor 4E-like 3; 4EHP |
应用说明
| 预测反应性说明 | Rat | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HL-60 | ||||||||
| 实际分子量 | ~ 30 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O60573 Human Eukaryotic translation initiation factor 4E type 2 Swiss-port # Q8BMB3 Mouse Eukaryotic translation initiation factor 4E type 2 |
|---|---|
| 基因名称 | EIF4E2 |
| 全名 | eukaryotic translation initiation factor 4E family member 2 |
| 生物功能 | Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. [UniProt] |
| 预测分子量 | 28 kDa |
| 翻译后修饰 | Ubiquitinated by ARIH1 (PubMed:14623119, PubMed:25624349). The consequences of ubiquitination are however unclear: according to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest (PubMed:25624349). According to another report ubiquitination leads to its subsequent degradation (PubMed:14623119). ISGylation enhances its cap structure-binding activity and translation-inhibition activity. |
检测图片 (1)
ARG56163 anti-eIF4E2 antibody WB image
Western blot: HL-60 cell lysate stained with ARG56163 anti-eIF4E2 antibody.
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