anti-HLA G antibody [G233]

产品描述: Mouse Monoclonal antibody [G233] recognizes HLA G
反应物种: Hu
应用: ELISA, FACS, IP
特异性: The clone G233 recognizes several isoforms of HLA-G expressed in all populations of extravillous trophoblast (cell columns, interstitial trophoblast, endovascular trophoblast, placental bed giant cells). HLA-G belongs to the nonclassical MHC Class I molecules (MHC Class Ib). G233 has been found not to cross-react with any other MHC Class I antigens (HLA-A, -B, -C, -E, -F).
宿主: Mouse
克隆: Monoclonal
克隆号: G233
同位型: IgG2a
靶点名称: HLA G

CAT.NO. : ARG10111

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [G233] recognizes HLA G
反应物种	Hu
应用	ELISA, FACS, IP
特异性	The clone G233 recognizes several isoforms of HLA-G expressed in all populations of extravillous trophoblast (cell columns, interstitial trophoblast, endovascular trophoblast, placental bed giant cells). HLA-G belongs to the nonclassical MHC Class I molecules (MHC Class Ib). G233 has been found not to cross-react with any other MHC Class I antigens (HLA-A, -B, -C, -E, -F).
宿主	Mouse
克隆	Monoclonal
克隆号	G233
同位型	IgG2a
靶点名称	HLA G
抗原物种	Human
抗原	HLA-A2.1/human beta2-microglobulin double transgenic mice were immunized with murine L cells transfected with both human beta2-microglobulin and HLA-G.
偶联标记	Un-conjugated
別名	HLA G antigen; MHC class I antigen G; HLA class I histocompatibility antigen, alpha chain G; MHC-G

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified from hybridoma culture supernatant by protein-A affinity chromatography.
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3135 Human HLA-G Swiss-port # P17693 Human HLA class I histocompatibility antigen, alpha chain G
基因名称	HLA-G
全名	major histocompatibility complex, class I, G
背景介绍	HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
生物功能	Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells. [UniProt]
研究领域	Immune System antibody
预测分子量	38 kDa

检测图片 (2)

ARG10111 anti-HLA G antibody [G233] IP image
Immunoprecipitation: HLA-G from HLA-G1 transfectants (LCL-HLA-G1) immunoprecipitated by ARG10106 anti-HLA G antibody [MEM-G/9] and protein G. HLA-G was stained with ARG10111 anti-HLA G antibody [G233] in cell lysate (Lane 1) and in the immunoprecipitate (Lane 2).
ARG10111 anti-HLA G antibody [G233] FACS image
Flow Cytometry: HLA-G transfectants stained with ARG10111 anti-HLA G antibody [G233], followed by APC-conjugated Goat anti-Mouse antibody.