anti-PLEKHA1 / TAPP1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG42988
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PLEKHA1 / TAPP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PLEKHA1 / TAPP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human PLEKHA1 / TAPP1. |
| 偶联标记 | Un-conjugated |
| 別名 | Pleckstrin homology domain-containing family A member 1; TAPP1; Tandem PH domain-containing protein 1; TAPP-1; PH domain-containing family A member 1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | K562 | ||||||
| 实际分子量 | ~ 46 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8BUL6 Mouse Pleckstrin homology domain-containing family A member 1 Swiss-port # Q9HB21 Human Pleckstrin homology domain-containing family A member 1 |
|---|---|
| 基因名称 | PLEKHA1 |
| 全名 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| 背景介绍 | This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Sep 2010] |
| 生物功能 | Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. [UniProt] |
| 细胞定位 | Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. [UniProt] |
| 预测分子量 | 46 kDa |
检测图片 (1)
ARG42988 anti-PLEKHA1 / TAPP1 antibody WB image
Western blot: K562 cell lysate stained with ARG42988 anti-PLEKHA1 / TAPP1 antibody at 1:1000 dilution.
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