anti-Prohibitin antibody [II-14-10]
![anti-Prohibitin antibody [II-14-10]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
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- 宿主:
- 克隆:
- 克隆号:
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- 靶点名称:
- 抗原物种:
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Brand:
Product Details
| 产品描述 | Mouse Monoclonal antibody [II-14-10] recognizes Prohibitin |
|---|---|
| 反应物种 | Hu, Ms, Rat, Pig |
| 应用 | FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | II-14-10 |
| 同位型 | IgG1 |
| 靶点名称 | Prohibitin |
| 抗原物种 | Rat |
| 抗原 | BALB/C mice were injected with purified Recombinant Rat Prohibitin protein. |
| 偶联标记 | Un-conjugated |
| 別名 | HEL-215; PHB1; Prohibitin; HEL-S-54e |
| 应用说明 | WB: 1/100 FACS: 1µg for 106 cells IHC-P: 1/50 - 1/100 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 形式 | Liquid |
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| 缓冲液 | PBS, 1% BSA and 0.05% Sodium azide |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 1% BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
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| 基因名称 | Phb |
| 全名 | prohibitin |
| 背景介绍 | This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| 生物功能 | Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging. [UniProt] |
| 产品亮点 | Related products: Prohibitin antibodies; Anti-Mouse IgG secondary antibodies; Related poster download: The Structure & Functions of Mitochondria.pdf |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Gene Regulation antibody; Metabolism antibody |
| 预测分子量 | 30 kDa |
克隆号文献
Identification of prohibitin 1 as a potential prognostic biomarker in human pancreatic carcinoma using modified aqueous two-phase partition system combined with 2D-MALDI-TOF-TOF-MS/MS.
Modulation of age-related insulin sensitivity by VEGF-dependent vascular plasticity in adipose tissues.
Prohibitins function as endogenous ligands for Siglec-9 and negatively regulate TCR signaling upon ligation.
WB / Human
GRSF1 regulates RNA processing in mitochondrial RNA granules.
WB / Human
All-trans retinoic acid treatment is associated with prohibitin expression in renal interstitial fibrosis rats.
IHC / Rat
Isoform-specific targeting of PKA to multivesicular bodies.
Proteomic analysis of myocardial tissue from the border zone during early stage post-infarct remodelling in rats.
WB / Rat
Mitochondrial comparative proteomics of human ovarian cancer cells and their platinum-resistant sublines.
WB, IHC-P / Human
PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation.
IHC-Fr / Mouse
Prohibitin as an oxidative stress biomarker in the eye.
WB / Bovine
Intrauterine growth restriction and postnatal high-protein diet affect the kidneys in adult rats.
WB / Rat
Extracellular growth factors and mitogens cooperate to drive mitochondrial biogenesis.
ICC/IF / Rat
Leishmania cell surface prohibitin: role in host-parasite interaction.
WB / Mouse
Cellular vimentin content regulates the protein level of hepatitis C virus core protein and the hepatitis C virus production in cultured cells.
WB / Virus
A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that prohibitin is involved in the synaptic pathology of schizophrenia.
WB, ICC/IF, IHC-P / Human, Rat
Development of the terminally differentiated state sensitizes epiphyseal chondrocytes to apoptosis through caspase-3 activation.
WB / Bird
Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites.
ChIP / Human
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