anti-Trypsin antibody [A16-N]

Key features and details

  • 产品描述: Rabbit Monoclonal antibody [A16-N] recognizes Trypsin
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: A16-N
  • 同位型: IgG
  • 靶点名称: Trypsin
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG10590
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Product Details
概述
产品描述Rabbit Monoclonal antibody [A16-N] recognizes Trypsin
反应物种Hu
应用WB
宿主Rabbit
克隆Monoclonal
克隆号A16-N
同位型IgG
靶点名称Trypsin
抗原物种Human
抗原Synthetic peptide around the N-terminus of Human pancreatic cationic trypsin
偶联标记Un-conjugated
別名Trypsin I; TRY4; TRY1; Serine protease 1; EC 3.4.21.4; Cationic trypsinogen; Trypsin-1; TRYP1; TRP1; Beta-trypsin
应用说明
应用建议
应用推荐稀释比
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液20 mM Tris-HCl (pH 8.0), 0.05% Sodium azide and 10 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂10 mg/ml BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5644 Human PRSS1

Swiss-port # P07477 Human Trypsin-1

基因名称PRSS1
全名protease, serine, 1 (trypsin 1)
背景介绍This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]
生物功能Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates. [UniProt]
预测分子量27 kDa
翻译后修饰Occurs in a single-chain form and a two-chain form, produced by proteolytic cleavage after Arg-122.
Sulfation at Tyr-154 increases selectivity towards basic versus apolar residues at the P2' position of inhibitors that bind in a substrate-like fashion. Although the increase in selectivity is relatively small, it may facilitate digestion of a broader range of dietary proteins.
检测图片 (1)
  • ARG10590 anti-Trypsin antibody [A16-N] WB image

    Western blot: 20 ng, 40 ng, 100 ng, and 200 ng of Human trypsin stained with ARG10590 anti-Trypsin antibody [A16-N].

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