Cathepsin K Rabbit Monoclonal Antibody(ARA875)

Key features and details

  • Reactivity:Human, Mouse, Rat
  • Application:WB, IHC
  • Host:Rabbit
  • Clonality:Monoclonal
  • Target:Cathepsin K
  • Brand:
CAT.NO. : ARA6701
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Product Details
Background
Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
Application

Application

Dilution Ratio

WB

1:500 - 1:1000

IHC

1:50 - 1:200

Overview

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within human Cathepsin H/K/L/V. The exact sequence is proprietary

Purification Method

The antibody was purified by immunogen affinity chromatography

Clonality

Monoclonal

Form

Liquid in PBS, pH 7.4, containing 50% glycerol, 0.2% BSA and 0.01% sodium azide

Gene Symbols

CTSH; CTSK; CTSL1; CTSL2

Alternative Names

CPSB; Pro-cathepsin H; CTSO; CTSO2; Cathepsin K; Cathepsin O; Cathepsin O2; Cathepsin X; CTSL1; Cathepsin L1; Cathepsin L; Major excreted protein; MEP; CATL2; CTSL2; CTSU; Cathepsin L2; Cathepsin U; Cathepsin V

Gene IDs (Human)

1512; 1513; 1514; 1515

Gene IDs (Mouse)

13036; 13038; 13039

Gene IDs (Rat)

25425; 29175; 25697

Protein IDs (Human)

P09668; P43235; P07711; O60911

Protein IDs (Mouse)

P49935; P55097; P06797

Protein IDs (Rat)

P00786; O35186; P07154

Data

Western blot analysis of Cathepsin H/K/L/V expression in mouse liver (A), rat liver (B) whole cell lysates. (Predicted band size: 37 kD; Observed band size: 38 kD)

Immunohistochemical analysis of Cathepsin H/K/L/V staining in rat liver formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. Tyramide-AF488 (green) was used as the chromogen. The section was then counterstained with DAPI (blue).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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