CD138 Rabbit Monoclonal Antibody(ARB586)
Key features and details
- Reactivity:Human
- Application:IHC
- Host:Rabbit
- Clonality:Monoclonal
- Target:CD138
-
Brand:
CAT.NO. : ARB6878
RMB Please choose
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
CD138 (syndecan-1) is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans’ main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among nonhaematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma. CD138 is a sensitive and specific marker for identification of plasma cells and plasma cell differentiation within haematolymphoid tissues in benign and neoplastic conditions.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:100-1:200 |
Overview
|
Predicted Molecular Wt |
32kDa |
|
Species Cross-reactivity |
Human |
|
Applications |
IHC-P |
|
Purity |
ProA affinity purified IgG |
|
Form |
Liquid |
|
Swissprot ID |
P18227 |
|
Subcellular location |
Membrane and cytoplasm |
|
Recommended Method |
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18℃-25℃) for 30 minutes. |
|
Immunogen |
Synthetic peptide. |
Data
Immunohistochemical staining of human plasmacytoma using CD138 Rabbit Monoclonal Antibody(ARB586)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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