Cytokeratin 13 Rabbit Monoclonal Antibody(ARA854)

Key features and details

  • Reactivity:Human, Mouse
  • Application:IHC
  • Host:Rabbit
  • Clonality:Monoclonal
  • Target:Cytokeratin 13
  • Brand:
CAT.NO. : ARA6680
RMB Please choose
RMB Please choose
Size:
1mL
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa.
Application

Application

Dilution Ratio

IHC-P

1:100 - 1:200

Overview

Antibody Type

Recombinant Rabbit monoclonal Antibody

Immunogen

Synthetic peptide within Human Cytokeratin 13 aa 111 - 160 / 458

Species Reactivity

Human, Mouse

Molecular Weight

Predicted band size: 50 kDa

Positive Control

A431 cell lysate, HaCaT cell lysate, Mouse lung tissue lysate, Mouse skin tissue lysate, A431, hybrid fish (crucian - carp) brain tissue lysates, Hela, A549, human tonsil tissue, human lung squamous cell tissue, human cervical carcinoma tissue

Conjugation

unconjugated

Form

Liquid

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide

Isotype

IgG

Purification Method

Protein A affinity purified

Data

Immunohistochemical analysis of paraffin-embedded human lung squamous cell tissue with Cytokeratin 13 Rabbit Monoclonal Antibody(ARA854).

Immunohistochemical analysis of paraffin-embedded human cervical carcinoma tissue with Cytokeratin 13 Rabbit Monoclonal Antibody(ARA854).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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