GPCR19 Rabbit Polyclonal Antibody
Key features and details
- Reactivity:Human
- Application:WB
- Host:Rabbit
- Clonality:Polyclonal
- Target:GPCR19
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Brand:
CAT.NO. : ARA6673
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Product Details
Background
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Application
|
Application |
Dilution Ratio |
|
WB |
1:500 - 1:1000 |
Overview
|
Immunogen |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GPCR19. The exact sequence is proprietary. |
|
Purification |
The antibody was purified by immunogen affinity chromatography. |
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Clonality |
Polyclonal |
|
Form |
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
|
Gene Symbol |
GPBAR1 |
|
Alternative Names |
TGR5; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37 |
|
Entrez Gene (Human) |
151306 |
Data
Western blot analysis of GPCR19 expression in Hela (A), HCT116 (B), A549 (C) whole cell lysates. (Predicted band size: 35 kD; Observed band size: 60 kD)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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