Human Beta Amyloid 1-40 antibody pair (ARA954/ARA991)
Key features and details
- Reactivity:Human
- Application:Sandwich ELISA
- Antigen Species:Human
- Gene name: APP
- Target:Beta Amyloid 1-40 Antibody
-
Brand:
CAT.NO. : ARA6876
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
Background
Amyloid-beta (1-40), abbreviated as Aβ(1-40), is a 40-residue peptide derived from the amyloid precursor protein (APP) and is involved in the pathogenesis of Alzheimer's disease (AD). It is one of the two main C-terminal variants of the amyloid-beta peptide, along with Aβ(1-42). Both Aβ(1-40) and Aβ(1-42) form aggregates and deposits in the AD brain, contributing to the formation of senile plaques. Unaggregated soluble Aβ(1-40) can also exhibit toxic effects and influence behavior and memory. Additionally, Aβ(1-40) has been shown to interact with synaptic structures such as postsynaptic density-95 (PSD-95), leading to its degradation and affecting synaptic function.
Application
The Beta Amyloid 1-40 Matched Antibody Pair is expertly designed for immunoassay technologies and high-throughput ELISA platforms that require specifically labeled antibody pairs. These pairs can be customized with a variety of labels such as fluorophores, biotin, and beads. Compatible technologies include MSD, Luminex, Quanterix Simoa, Alpha Technology etc.
Component
| Products include | Catalog No. | Isotype | Quantity | Form |
|---|---|---|---|---|
| Beta Amyloid Antibody （ARA6798） | KC-1732 | Mouse IgG2a | 100μg | Liquid |
| Beta Amyloid 1-40 Antibody （ARA6889） | KC-108 | Mouse IgG2b | 100μg | Liquid |
| Human beta Amyloid 1-40 polypeptide | PE-001 | / | 20μg | Liquid |
Overview
|
Antibody Pair Specificity |
Beta Amyloid 1-40 |
|
Species Reactivity |
Human |
|
Protein Standard |
Human beta Amyloid 1-40 polypeptide [PE-001] |
|
Target Antigen |
Protein name: amyloid beta precursor protein; Gene name: APP; UniProt Accession: P05067; Organism: Homo sapiens (Human) |
|
Cross Reactivity |
Not Tested |
Data
Sandwich ELISA Microtiter wells were coated with ARA6798 at 2 µg/mL as the capture antibody. Recommbinant Beta Amyloid 1-40 protein (Cat #: PE-001) was used as the antigen. 200 ng/mL biotin conjugated Beta Amyloid 1-40 Antibody (ARA6889) was used as the detection antibody. Result: ARA6798 and ARA6889 can be used as a matched antibody pair to detect and quantify the concentration of Human Beta Amyloid 1-40 with high specificity.
Storage
Shipped at ambient temperature or with ice packs. Avoid repeated freeze-thaw cycles.
Upon receipt,
* 1 month when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Upon receipt,
* 1 month when stored at 2 to 8 °C
* 12 months when aliquoted and stored at -20 °C or below
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
New Products
