Human CYP3A4 ELISA Kit
Key features and details
- Specificity:46.875pg/ml
- Detection Range: 78.125-5000pg/ml
- Sample Types: Plasma, tissue homogenates and other biological fluids in vitro
- Species:Human
- Detection Method: Sandwich ELISA
- Target:CYP3A4
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Brand:
CAT.NO. : ARE6633
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Product Details
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Overview
|
Name |
Human CYP3A4 (Cytochrome P450 3A4) ELISA Kit |
|
Synonyms |
CYP3A4 ELISA Kit, Cytochrome P450 3A4 ELISA Kit, CYP3A3 CYPIlIA3 ELISA Kit, CYPIlIA4 ELISA Kit, Nifedipine ELISA Kit, 8-cineole 2-exo-monooxygenase ELISA Kit, Albendazole monooxygenase ELISA Kit, Albendazole sulfoxidase ELISA Kit, Cytochrome P450 |
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Species Reactivity |
Human |
|
Size |
96T |
|
UNIPROT ID |
P08684 |
|
Application |
The human cytochrome P450 3A4 (CYP3A4) enzyme-linked immunosorbent assay (ELISA) kit can quantitatively determine the concentration of human cytochrome P450 3A4 (CYP3A4) in plasma, tissue homogenates and other biological fluids in vitro |
|
Detection Method |
Sandwich ELISA |
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Detection Range |
78.125 - 5000pg/ml |
|
Sensitivity |
< 46.875pg/ml |
Data
Standard curve
Storage
Shipped and store at 4°C for 6 month.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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