Human IGFBP6 recombinant protein (His-tagged, C-ter)
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CAT.NO. : ARG70259
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Product Details
概述
| 产品描述 | HEK293 expressed, His-tagged (C-ter) Human IGFBP6 recombinant protein. |
|---|---|
| 反应物种 | Hu |
| 应用 | Binding, SDS-PAGE |
| 靶点名称 | IGFBP6 |
| 物种 | Human |
| A.A. 序列 | Met1 - Gly240 of Human IGFBP6 (NP_002169.1) with 6X His tag at the C-terminus. |
| 表达系统 | HEK293 |
| 別名 | IBP-6; IGF-binding protein 6; IGFBP-6; IBP6; Insulin-like growth factor-binding protein 6 |
应用说明
| 应用说明 | Binding activity test: Measured by its binding ability in a functional ELISA. Immobilized recombinant human IGFBP6 at 1 ug/ml (100 µl/well) can bind recombinant human IGF1 with a linear range of 30-250 ng/ml. |
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属性
| 形式 | Powder |
|---|---|
| 纯化说明 | 0.22 µm filter sterilized. Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P24592 Human Insulin-like growth factor-binding protein 6 |
|---|---|
| 基因名称 | IGFBP6 |
| 全名 | insulin-like growth factor binding protein 6 |
| 生物功能 | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylated on one site only in the region AA 143-168 in cerebrospinal fluid. [UniProt] |
检测图片 (1)
ARG70259 Human IGFBP6 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70259 Human IGFBP6 recombinant protein (His-tagged, C-ter).
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