Human pTau217 Antibody Pair(ARA957/ARA958)
Key features and details
- Reactivity:Human
- Application:Sandwich ELISA
- Host:Mouse
- Clonality:Monoclonal
- Target:pTau217
-
Brand:
CAT.NO. : ARA6808
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Size:
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Product Details
Background
Plasma p - tau217 is a biomarker associated with Alzheimer's disease (AD) pathology. Research has shown that plasma p - tau217 is a sensitive marker of the clinical manifestation and progression of AD, including amyloid accumulation, tau burden, brain atrophy, and physical degradation. It has been found to be a potential non - invasive biomarker of AD, with high diagnostic accuracy in differentiating AD from other neurodegenerative diseases. Plasma p - tau217 has also been associated with longitudinal increases in Aβ PET uptake and cognitive decline in Aβ - positive clinically unimpaired individuals. Additionally, higher baseline p - tau217 levels have been linked to greater future tau PET pathology burden and worse future memory performance. These findings suggest that plasma p - tau217 could serve as a minimally invasive diagnostic and prognostic biomarker for AD, with potential utility in clinical practice and trials.
Component
| Products include | Catalog No. | Isotype | Quantity | Form |
|---|---|---|---|---|
| pTau217 Mouse Monoclonal Antibody(ARA957) | ARA6806 | Mouse IgG1 | 100μg | Liquid |
| Tau (S422) Mouse Monoclonal Antibody(ARA958) | ARA6807 | Mouse IgG2a | 100μg | Liquid |
| Recombinant Human p-Tau217 Protein | AXP6612 | / | 20μg | Liquid |
Overview
|
Antibody pair specificity |
pTau217 |
|
Species reactivity |
Human |
|
Protein standard |
Recombinant Human p-Tau217 Protein |
|
Target antigen |
Protein name: Microtubule-associated protein tau |
|
Cross reactivity |
Not Tested |
Data
Sandwich ELISA
Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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