IFITM1 Mouse Monoclonal Antibody(ARA888)

Key features and details

Reactivity:Human
Application:IHC
Host:Mouse
Clonality:Monoclonal
Target:IFITM1

Brand:

CAT.NO. : ARA6715

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Size:

1mL

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Product Details

Background

IFITM1(interferon induced transmembrane protein), also named DSPA2a and interferon-induced protein 17 (IFI17), belongs to the CD225 family. It has two transmembrane domain and serves as an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, influenza A H1N1 virus, West Nile virus (WNV), and dengue virus , by inhibiting the early steps of replication. IFITM proteins are recently identified as viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. Also they serve as important components of the innate immune system to restrict HIV-1 infection.

Application

Application	Dilution Ratio
IHC-P	1:200-1:1000

Overview

Host/Isotype	Mouse / IgG2a
Antibody Class	Monoclonal
Product Type	Antibody
Full Name	interferon induced transmembrane protein 1 (9-27)
Synonyms	9 27, CD225, IFl17, IFITM1, IFITM1-Specific, Interferon induced protein 17, Leu 13 antigen, LEU13
Calculated Molecular Weight	14 kDa
Observed Molecular Weight	14 - 17 kDa
Gene Name	IFITM1
RRID	AB_2233405
Conjugation	Unconjugated
Form	Liquid
Purification Method	Protein A purification
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol, pH 7.3