KDSR Rabbit Polyclonal Antibody

Key features and details

  • Reactivity:Human, Mouse
  • Application:WB
  • Host:Rabbit
  • Clonality:Polyclonal
  • Target:KDSR
  • Brand:
CAT.NO. : ARA6875
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Product Details
Background
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
Application

Application

Dilution Ratio

WB

1:500 - 1:1000

Overview

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human KDSR. The exact sequence is proprietary.

Purification Method

The antibody was purified by immunogen affinity chromatography.

Clonality

Polyclonal

Product Form

Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Gene Name

KDSR

Alternative Names

FVT1; 3-ketodihydrosphingosine reductase; KDS reductase; 3-dehydrosphinganine reductase; Follicular variant translocation protein 1; FVT-1

Human Gene ID

2531

Mouse Gene ID

70750

Human Protein ID

Q06136

Mouse Protein ID

Q6GV12

Storage
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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