LRG1 Mouse Monoclonal Antibody (C-5)
Key features and details
- Reactivity:Mouse
- Application:WB, IP, IF,ELISA
- Host:Mouse
- Clonality:Monoclonal
- lsotype:IgG2b
- Target Name:LRG1
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Brand:
CAT.NO. : ARA0105
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Size:
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Product Details
Background
LRG1 (leucine - rich α - 2 - glycoprotein), also known as LRG, is a 347 amino acid secreted protein that contains eight LRR (leucine - rich) repeats and one LRRCT domain. The leucine - rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein - protein interaction, signal transduction, cell adhesion and development. Found mainly in plasma, LRG1 is expressed during granulocyte differentiation. The gene that encodes LRG1 consists of nearly 3,000 bases and maps to human chromosome 19p13.3. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig - like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).
Application
LRG1 (C - 5) is recommended for detection of LRG1 of mouse origin by Western Blotting (starting dilution 1:100, dilution range 1:100 - 1:1000), immunoprecipitation [1 - 2 µg per 100 - 500 µg of total protein (1 ml of cell lysate)], immunofluorescence (starting dilution 1:50, dilution range 1:50 - 1:500) and solid phase ELISA (starting dilution 1:30, dilution range 1:30 - 1:3000).
Data
LRG1 (C - 5) . Western blot analysis of LRG1 expression in non - transfected [unclear text] (A) and mouse LRG1 transfected (B) 293T whole cell lysates.
LRG1 (C - 5) . Western blot analysis of LRG1 expression in mouse plasma tissue extract.
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