MEOX2 Rabbit Polyclonal Antibody

Key features and details

Reactivity:Human, Mouse, Rat
Application:WB, IHC, ICC
Host:Rabbit
Clonality:Polyclonal
Target:MEOX2

Brand:

CAT.NO. : ARA6797

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Size:

50μL 100μL

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Product Details

Background

Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity). Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000). May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Application

Application	Dilution Ratio
WB	1:200-1:500
IHC-P	1:1000-1:5000
ICC	1:50-1:100

Overview

Immunogen	Synthetic peptide within human MEOX2 aa 255-304/304
Species Reactivity	Human, Mouse, Rat
Validated Applications	WB, IHC-P, IF-Cell
Molecular Weight	Predicted band size: 34 kDa
Positive Control	Rat kidney tissue lysates, mouse embryo tissue, rat embryo tissue, A375
Conjugation	unconjugated
RRID	AB_3071153
Form	Liquid
Concentration	1ug/ul
Storage Buffer	1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide
Isotype	IgG
Purification Method	Immunogen affinity purified
Subcellular Location	Nucleus
UNIPROT	SwissProt: P50222 Human; SwissProt: P32443 Mouse; SwissProt: P39020 Rat
Synonyms	GAX antibody; Growth arrest-specific homeobox antibody; Homeobox protein MOX 2 antibody; Homeobox protein MOX-2 antibody; meox2 antibody; MEOX2_HUMAN antibody; Mesenchyme homeobox 2 antibody; MOX2 antibody