PAX-5 Rabbit Monoclonal Antibody(ARM870)
Key features and details
- Target:
- Clone ID:
- Host Species:
- Species Cross-reactivity:
- Applications:
- Dilution:
- Clonality:
- Storage:
-
Brand:
CAT.NO. : ARM6660
RMB Please choose
RMB Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
PAX-5 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. The PAX-5 gene encodes the B-cell lineage specific activator protein (BSAP), whose expression is limited to early stages of B-cell differentiation. Anti-PAX-5 is useful in differentiating between classic Hodgkin's lymphoma versus multiple myeloma and solitary plasmacytoma, as the protein is expressed in mature and precursor B-cell non-Hodgkin's lymphomas/leukemias while being absent from the other two conditions. Diffuse large B-cell lymphomas are positive for PAX-5, with the exception of those with terminal B-cell differentiation, and T-cell neoplasms do not stain with Anti-PAX-5.
Application
|
Application |
Dilution Ratio |
|
IHC |
1:50 - 1:200 |
Overview
|
Molecular Weight |
42,149 Da |
|
Chromosome Location |
Chromosome: 9; NC_000009.11 (36838531..37034476, complement); Location: 9p13 |
|
OMIM |
167414 |
|
3D Structure |
ModBase 3D Structure for Q02548 |
|
Clonality |
Monoclonal |
|
Isotype |
IgG |
|
Host |
Rabbit |
|
Species Reactivity |
Human |
|
Specificity |
PAX-5 |
|
Purity/Purification |
Purified |
|
Form/Format |
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
|
Immunogen |
Recombinant Protein |
Data
Immunohistochemical staining of human tonsil tissue using PAX-5 Rabbit Monoclonal Antibody (ARM870)
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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