Podocalyxin Mouse Monoclonal Antibody(ARA996)
Key features and details
- Reactivity:Human
- Application:IHC, IF, ELISA
- Host:Mouse
- Clonality:Monoclonal
- Target:Podocalyxin
-
Brand:
CAT.NO. : ARA6901
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Size:
Trail, Bulk size or Custom requests Please contact us
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Product Details
Background
Podocalyxin, also known as podocalyxin-like protein 1 (PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers. Podocalyxin is a protein with a peptide bone of ∼55.5 kDa that undergoes a post‐translational glycosylation, the different molecular mass of podocalyxin indicates the extent and variability of glycosylation patterns (PMID: 17092254).
Application
|
Application |
Dilution Ratio |
|
IHC |
1:500-1:2000 |
Overview
|
Immunogen |
Recombinant human TRA-1-60 protein |
|
Host/Isotype |
Mouse / IgG2a |
|
Antibody Class |
Monoclonal |
|
Product Type |
Antibody |
|
Alternative Names |
PODXL, 4A3C7, GCTM 2 antigen, GCTM-2 antigen, Gp200 |
|
Calculated Molecular Weight |
526 aa, 55 kDa |
|
Observed Molecular Weight |
60-70 kDa |
|
GenBank Protein Accession |
BC093730 |
|
Gene Name |
Podocalyxin |
|
Gene ID (NCBI) |
5420 |
|
RRID |
AB_2935335 |
|
Conjugation Type |
Unconjugated |
|
Form |
Liquid |
|
Purification Method |
Protein A purification |
|
UNIPROT ID |
O00592 |
|
Storage Buffer |
PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
Data
Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using Podocalyxin Mouse Monoclonal Antibody(ARA996).
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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