Recombinant Human Cuteaneous T-cell Attracting Chemokine/CCL27
CAT.NO. : ARP6676
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Background
CCL27, also named IL-11 R-alpha-locus chemokine (ILC) , Skinkine, ESkine and cutaneous T-cell-attracting chemokine (CTACK) , is a small cytokine belonging to the CC chemokine family. CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin and it elicits its chemotactic effects by binding to the chemokine receptor CCR10. CCL27 can attract skin-associated memory T-lymphocytes. Studies showed it may play a role in mediating homing of lymphocytes to cutaneous sites and cell migration during embryogenesis. Mature human CCL27 is an 88 amino acid (a.a.) protein that shares 56% a.a. sequence identity with murine. Recombinant Human CTACK is a 10.2kDa protein containing 88 amino acid residues.
