Recombinant Human Fibronectin Fragment
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CAT.NO. : ARP6750
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Product Details
Background
Fibronectin (FN) is a large, modular glycoprotein that generates a polymeric fibrillar network in the extracellular matrix (ECM) , and forms soluble, disulfide-linked dimeric protomers in plasma and other body fluids. Fibronectin is a ligand for many molecules, including fibrin, heparin, chondroitin sulfate, collagen/gelatin, and integrin. It is involved in multiple cellular processes such as cell adhesion/migration, blood clotting, morphogenesis, tissue repair, and cell signaling.
Recombinant Human Fibronectin fragment is a recombinant fibronectin fragment composed of three functional domains: the cell-binding domain (C-domain) , heparin-binding domain (H-domain) , and CS-1 sequence. The fragment can improve the efficiency of retroviral-mediated gene transduction by helping the co-localization of target cells and virions
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