TaR-1 Rabbit Polyclonal Antibody

Key features and details

Reactivity:Human, Mouse, Rat
Application:WB
Host:Rabbit
Clonality:Polyclonal
Target:TaR-1

Brand:

CAT.NO. : ARA6729

RMB Please choose

Size:

50μL 100μL

Trail, Bulk size or Custom requests Please contact us

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Product Details

Background

TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.

Application

Application	Dilution Ratio
WB	1:500 - 1:1000

Overview

Immunogen	KLH-conjugated synthetic peptide of human TaR-1. The exact sequence is proprietary
Purification	The antibody was purified by immunogen affinity chromatography
Clonality	Polyclonal
Form	Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide
Gene Symbol	TAAR1
Alternative Names	TA1; TAR1; TRAR1; Trace amine-associated receptor 1; TaR-1; Trace amine receptor 1
Entrez Gene (Human)	134864;
Entrez Gene (Mouse)	111174;
Entrez Gene (Rat)	113914;
SwissProt (Human)	Q96RJ0;
SwissProt (Mouse)	Q923Y8;
SwissProt (Rat)	Q923Y9;