anti-Bcl G antibody
CAT.NO. : ARG54958
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概述
产品描述 | Rabbit Polyclonal antibody recognizes Bcl G |
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反应物种 | Hu |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Bcl G |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 194-229 of Human Bcl G. |
偶联标记 | Un-conjugated |
別名 | BCLG; Bcl2-L-14; Apoptosis regulator Bcl-G; Apoptosis facilitator Bcl-2-like protein 14 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | K562 |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide |
抗菌剂 | 0.09% (W/V) Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q9BZR8 Human Apoptosis facilitator Bcl-2-like protein 14 |
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基因名称 | BCL2L14 |
全名 | BCL2-like 14 (apoptosis facilitator) |
背景介绍 | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009] |
生物功能 | Plays a role in apoptosis. [UniProt] |
细胞定位 | Cytoplasm. Isoform 2: Endomembrane system. Note=Predominantly localized to cytosolic organelles |
研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody |
预测分子量 | 37 kDa |
翻译后修饰 | Phosphorylated by MELK, leading to inhibit its pro-apoptotic function. |
