anti-CD197 / CCR7 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes CD197 / CCR7
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: CD197 / CCR7
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human CD197 / CCR7.
  • Brand:
CAT.NO. : ARG58043
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes CD197 / CCR7
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称CD197 / CCR7
抗原物种Human
抗原Synthetic peptide derived from Human CD197 / CCR7.
偶联标记Un-conjugated
別名C-C chemokine receptor type 7; CD197; CD antigen CD197; CCR-7; CC-CKR-7; BLR2; CMKBR7; C-C CKR-7; MIP-3 beta receptor; EBV-induced G-protein coupled receptor 1; EBI1; Epstein-Barr virus-induced G-protein coupled receptor 1; CDw197
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
IP1:50
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Daudi and MCF-7
实际分子量~ 42 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 1236 Human CCR7

GeneID: 12775 Mouse CCR7

Swiss-port # P32248 Human C-C chemokine receptor type 7

Swiss-port # P47774 Mouse C-C chemokine receptor type 7

基因名称CCR7
全名chemokine (C-C motif) receptor 7
背景介绍The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
生物功能Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. [UniProt]
细胞定位Cell membrane > Multi-pass membrane protein. [UniProt]
预测分子量43 kDa
检测图片 (3)
  • ARG58043 anti-CD197 / CCR7 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG58043 anti-CD197 / CCR7 antibody (green). DAPI (blue) nuclear stain.

  • ARG58043 anti-CD197 / CCR7 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human spleen tissue stained with ARG58043 anti-CD197 / CCR7 antibody.

  • ARG58043 anti-CD197 / CCR7 antibody WB image

    Western blot: Daudi and MCF-7 cell lysates stained with ARG58043 anti-CD197 / CCR7 antibody.

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