anti-CD52 antibody [HI186]

产品描述: Mouse Monoclonal antibody [HI186] recognizes CD52
反应物种: Hu
应用: CyTOF®-candidate, FACS, IHC-P
特异性: The clone HI186 reacts with CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract. HLDA VI; WS Code BP 523HLDA VI; WS Code T 6T-057
宿主: Mouse
克隆: Monoclonal
克隆号: HI186
同位型: IgG2b
靶点名称: CD52

CAT.NO. : ARG62881

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Size:

100 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [HI186] recognizes CD52
反应物种	Hu
应用	CyTOF®-candidate, FACS, IHC-P
特异性	The clone HI186 reacts with CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety; mature CD52 molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract. HLDA VI; WS Code BP 523 HLDA VI; WS Code T 6T-057
宿主	Mouse
克隆	Monoclonal
克隆号	HI186
同位型	IgG2b
靶点名称	CD52
抗原物种	Human
抗原	Human tonsil
偶联标记	Un-conjugated
別名	He5; CAMPATH-1 antigen; Human epididymis-specific protein 5; Cambridge pathology 1 antigen; CDw52; Epididymal secretory protein E5; CDW52; CD antigen CD52

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purified by protein A
纯度	> 95% (by SDS-PAGE)
缓冲液	PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂	15 mM Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 1043 Human CD52 Swiss-port # P31358 Human CAMPATH-1 antigen
基因名称	CD52
全名	CD52 molecule
背景介绍	CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.
生物功能	May play a role in carrying and orienting carbohydrate, as well as having a more specific role. [UniProt]
产品亮点	Related products: CD52 antibodies; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies
研究领域	Immune System antibody
预测分子量	7 kDa

检测图片 (2)

ARG62881 anti-CD52 antibody [HI186] FACS image
Flow Cytometry: Patient sample with Acute Lymphoblastic Leukemia (CD52 positive cALL) stained with ARG62881 anti-CD52 antibody [HI186], followed by incubation with PE-labelled secondary antibody.
ARG62881 anti-CD52 antibody [HI186] FACS image
Flow Cytometry: Patient sample with Acute Lymphoblastic Leukemia (CD52 positive cALL) stained with ARG62881 anti-CD52 antibody [HI186], followed by incubation with PE-labelled secondary antibody.

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