anti-CD99 antibody [3B2/TA8] (APC)

Key features and details

  • 产品描述: APC-conjugated Mouse Monoclonal antibody [3B2/TA8] recognizes CD99
  • 反应物种: Hu
  • 应用: FACS
  • 特异性: The mouse monoclonal antibody 3B2/TA8 recognizes CD99, an approximately 32 kDa sialoglycoprotein expressed on the surface of many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 3B2/TA8
  • 同位型: IgG2a, kappa
  • 靶点名称: CD99
  • Brand:
CAT.NO. : ARG42266
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Product Details
概述
产品描述APC-conjugated Mouse Monoclonal antibody [3B2/TA8] recognizes CD99
反应物种Hu
应用FACS
特异性The mouse monoclonal antibody 3B2/TA8 recognizes CD99, an approximately 32 kDa sialoglycoprotein expressed on the surface of many cell types, with particularly strong expression on Ewing´s sarcoma and peripheral primitive neuroectodermal tumors. Within the hematopoietic system, CD99 is expressed on virtually all cell types except granulocytes.
宿主Mouse
克隆Monoclonal
克隆号3B2/TA8
同位型IgG2a, kappa
靶点名称CD99
抗原物种Human
抗原Human thymocytes.
偶联标记APC
別名12E7; CD99 antigen; MIC2X; MIC2Y; CD antigen CD99; MSK5X; Protein MIC2; MIC2; T-cell surface glycoprotein E2; HBA71; E2 antigen
应用说明
应用建议
应用推荐稀释比
FACS10 µl / 100 µl of whole blood or 10^6 cells
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified
缓冲液PBS and 15 mM Sodium azide.
抗菌剂15 mM Sodium azide
存放说明Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 4267 Human CD99

Swiss-port # P14209 Human CD99 antigen

基因名称CD99
全名CD99 molecule
背景介绍The protein encoded by this gene is a cell surface glycoprotein involved in leukocyte migration, T-cell adhesion, ganglioside GM1 and transmembrane protein transport, and T-cell death by a caspase-independent pathway. In addition, the encoded protein may have the ability to rearrange the actin cytoskeleton and may also act as an oncosuppressor in osteosarcoma. This gene is found in the pseudoautosomal region of chromosomes X and Y and escapes X-chromosome inactivation. There is a related pseudogene located immediately adjacent to this locus. [provided by RefSeq, Mar 2016]
生物功能Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity). [UniProt]
细胞定位Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量19 kDa
翻译后修饰Extensively O-glycosylated. [UniProt]
检测图片 (1)
  • ARG42266 anti-CD99 antibody [3B2/TA8] (APC) FACS image

    Flow Cytometry: Human peripheral blood cells stained with ARG42266 anti-CD99 antibody [3B2/TA8] (APC).

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