anti-CEP290 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG65094
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes CEP290 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P |
| 特异性 | Despite similarity of the immunizing peptide with the mouse protein, this antibody was demonstrated to weak for mouse Cep290. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CEP290 |
| 抗原物种 | Human |
| 抗原 | C-RNSKHLKQQQYRAEN |
| 偶联标记 | Un-conjugated |
| 別名 | NPHP6; rd16; Bardet-Biedl syndrome 14 protein; JBTS5; Tumor antigen se2-2; POC3; SLSN6; Nephrocystin-6; LCA10; BBS14; Centrosomal protein of 290 kDa; Cancer/testis antigen 87; Cep290; 3H11Ag; CT87; MKS4 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008] |
| 研究领域 | Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 290 kDa |
| 翻译后修饰 | Ubiquitinated. May undergo monoubiquitination; monoubiquitination is inhibited in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock, but does not cause it displacement from centriolar satellites. |
检测图片 (2)
ARG65094 anti-CEP290 antibody ICC/IF image
Immunofluorescence: OPCT-1 (A) and MDA468 (B) cells stained with ARG65094 anti-CEP290 antibody (red) at 2.5 µg/ml dilution, overnight. DAPI (blue) for nuclear staining.
ARG65094 anti-CEP290 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG65094 anti-CEP290 antibody at 5 µg/ml dilution followed by HRP-staining.
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