anti-DSCR2 / PSMG1 antibody
产品描述 | Goat Polyclonal antibody recognizes DSCR2 / PSMG1 |
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反应物种 | Hu |
预测物种 | Ms, Rat, Cow, Dog |
应用 | FACS, ICC/IF |
特异性 | This antibody is expected to recognize both reported isoforms (NP_003711.1; NP_982257.1. |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | DSCR2 / PSMG1 |
抗原物种 | Human |
抗原 | C-KLMTTNEIQSNIYT |
偶联标记 | Un-conjugated |
別名 | Chromosome 21 leucine-rich protein; PAC-1; PAC1; Down syndrome critical region protein 2; C21-LRP; DSCR2; LRPC21; C21LRP; Proteasome assembly chaperone 1 |
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
数据库连接 | |
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基因名称 | PSMG1 |
全名 | proteasome (prosome, macropain) assembly chaperone 1 |
生物功能 | Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Signaling Transduction antibody |
预测分子量 | 33 kDa |
翻译后修饰 | Degraded by the proteasome upon completion of 20S proteasome maturation. |
ARG64852 anti-DSCR2 / PSMG1 antibody ICC/IF image
Immunofluorescence: Paraformaldehyde fixed A431 cells permeabilized with 0.15% Triton. Cells were stained with ARG64852 anti-DSCR2 / PSMG1 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.
ARG64852 anti-DSCR2 / PSMG1 antibody FACS image
Flow Cytometry: Paraformaldehyde-fixed Jurkat cells permeabilized with 0.5% Triton. Cells were stained with ARG64852 anti-DSCR2 / PSMG1 antibody (blue line) at 10 µg/ml dilution for 1 hour, followed by incubation with Alexa FluorR 488 labelled secondary antibody. IgG control: Unimmunized goat IgG (black line).
ARG64852 anti-DSCR2 / PSMG1 antibody ICC/IF image
Immunofluorescence: Paraformaldehyde fixed U2OS cells permeabilized with 0.15% Triton. Cells were stained with ARG64852 anti-DSCR2 / PSMG1 antibody (green) at 10 µg/ml dilution for 1 hour. DAPI (blue) for nuclear staining. Negative control: Unimmunized goat IgG (green) at 10 µg/ml dilution.
