anti-ELAVL3 / HUC antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ELAVL3 / HUC
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ELAVL3 / HUC
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human ELAVL3 / HUC
  • Brand:
CAT.NO. : ARG56319
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ELAVL3 / HUC
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ELAVL3 / HUC
抗原物种Human
抗原Synthetic peptide of Human ELAVL3 / HUC
偶联标记Un-conjugated
別名Paraneoplastic limbic encephalitis antigen 21; HUCL; HuC; Hu-antigen C; PLE21; ELAV-like protein 3; Paraneoplastic cerebellar degeneration-associated antigen; HUC
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse spinal cord
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 15571 Mouse ELAVL3

GeneID: 1995 Human ELAVL3

Swiss-port # Q14576 Human ELAV-like protein 3

Swiss-port # Q60900 Mouse ELAV-like protein 3

基因名称ELAVL3
全名ELAV like neuron-specific RNA binding protein 3
背景介绍A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance. [UniProt]
预测分子量40 kDa
检测图片 (2)
  • ARG56319 anti-ELAVL3 / HUC antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG56319 anti-ELAVL3 / HUC antibody at 1:200 dilution.

  • ARG56319 anti-ELAVL3 / HUC antibody WB image

    Western blot: Mouse spinal cord lysate stained with ARG56319 anti-ELAVL3 / HUC antibody.

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