anti-Homer 1 antibody [1F3]
![anti-Homer 1 antibody [1F3]](/upload/image/products/ARG56984_WB_1_210_205.jpg)
![anti-Homer 1 antibody [1F3]](/upload/image/products/ARG56984_WB_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG56984
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [1F3] recognizes Homer 1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1F3 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | Homer 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-354 of Human Homer1. |
| 偶联标记 | Un-conjugated |
| 別名 | HOMER; SYN47; Ves-1; Homer-1; HOMER1A; Homer protein homolog 1; HOMER1C; HOMER1B |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HOMER1 |
| 全名 | homer scaffolding protein 1 |
| 背景介绍 | This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008] |
| 生物功能 | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. [UniProt] |
| 预测分子量 | 40 kDa |
检测图片 (1)
ARG56984 anti-Homer 1 antibody [1F3] WB image
Western blot: 50 µg of Mouse brain stained with ARG56984 anti-Homer 1 antibody [1F3] at 1:1000.
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