anti-ICT1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes ICT1
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: ICT1
  • 抗原物种: Human
  • 抗原: KLH-conjugated synthetic peptide corresponding to aa. 153-179 (C-terminus) of Human ICT1.
  • Brand:
CAT.NO. : ARG55701
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes ICT1
反应物种Hu
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称ICT1
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 153-179 (C-terminus) of Human ICT1.
偶联标记Un-conjugated
別名39S ribosomal protein L58, mitochondrial; DS-1; MRP-L58; DS1; Peptidyl-tRNA hydrolase ICT1, mitochondrial; EC 3.1.1.29; Digestion substraction 1; Immature colon carcinoma transcript 1 protein
应用说明
应用建议
应用推荐稀释比
IHC-P1:25
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照K562
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide.
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 3396 Human ICT1

Swiss-port # Q14197 Human Peptidyl-tRNA hydrolase ICT1, mitochondrial

基因名称ICT1
全名immature colon carcinoma transcript 1
背景介绍The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
生物功能Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. [UniProt]
细胞定位Mitochondrion
预测分子量24 kDa
检测图片 (2)
  • ARG55701 anti-ICT1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colorectal carcinoma tissue stained with ARG55701 anti-ICT1 antibody at 1:25 dilution.

  • ARG55701 anti-ICT1 antibody WB image

    Western blot: 35 µg of K562 cell lysate stained with ARG55701 anti-ICT1 antibody.

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