anti-KLF4 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
-
Brand:
CAT.NO. : ARG55815
US＄ Please choose
US＄ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。
Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes KLF4 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF |
| 特异性 | This antibody recognize KLF4 and does not react to KLF4 alpha isoform. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 56CT5.1.6 |
| 同位型 | IgG1 |
| 靶点名称 | KLF4 |
| 抗原物种 | Human |
| 抗原 | KLF4 recombinant protein. |
| 偶联标记 | Un-conjugated |
| 別名 | GKLF; EZF; Epithelial zinc finger protein EZF; Krueppel-like factor 4; Gut-enriched krueppel-like factor |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | Purified PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLF4 |
| 全名 | Kruppel-like factor 4 (gut) |
| 背景介绍 | This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015] |
| 生物功能 | Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. [UniProt] |
| 细胞定位 | Nucleus. |
| 预测分子量 | 55 kDa |
检测图片 (2)
ARG55815 anti-KLF4 antibody ICC/IF image
Immunofluorescence: HeLa cells transfected with pMX constructs of Human KLF4 were analyzed at ~ 62 hours after transfection. Cells were stained with ARG55815 anti-KLF4 antibody at 5 µg/ml dilution.
ARG55815 anti-KLF4 antibody FACS image
Flow Cytometry: MCF7 cells stained with ARG55815 anti-KLF4 antibody (bottom histogram) or without primary antibody control (top histogram), followed by incubation with PE labelled secondary antibody.
New Products
