anti-MHC Class II antibody [NIMR-4]

Key features and details

  • 产品描述: Rat Monoclonal antibody [NIMR-4] recognizes MHC Class II
  • 反应物种: Ms
  • 应用: FACS, ICC/IF, IHC-Fr
  • 特异性: Mouse MHC Class II. The clone NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells.
  • 宿主: Rat
  • 克隆: Monoclonal
  • 克隆号: NIMR-4
  • 同位型: IgG2b, kappa
  • 靶点名称: MHC Class II
  • Brand:
CAT.NO. : ARG21056
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Product Details
概述
产品描述Rat Monoclonal antibody [NIMR-4] recognizes MHC Class II
反应物种Ms
应用FACS, ICC/IF, IHC-Fr
特异性Mouse MHC Class II. The clone NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells, and certain epithelial cells.
宿主Rat
克隆Monoclonal
克隆号NIMR-4
同位型IgG2b, kappa
靶点名称MHC Class II
抗原物种Mouse
偶联标记Un-conjugated
別名AI323765; H-2Ea; MHC-H2-Ea; H2-Ea; I-Ealpha; H-2 class II histocompatibility antigen, E-U alpha chain; Ia3; E-alpha-f; Ia-3
应用说明
应用建议
应用推荐稀释比
FACS
ICC/IFAssay-dependent
IHC-FrAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液BBS (pH 8.2)
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 100504404 Mouse H2-Ea-ps

Swiss-port # P14439 Mouse H-2 class II histocompatibility antigen, E-U alpha chain

基因名称H2-Ea-ps
全名histocompatibility 2, class II antigen E alpha, pseudogene
背景介绍This locus belongs to the class II major histocompatibility complex (MHC) family of genes, which encode immune response (Ia) antigens that function in the T-cell-dependent immune response. This family member has multiple haplotypes, some of which result in the production of an E-alpha subunit that combines with an E-beta subunit to form a functional E complex at the cell surface. Other haplotypes, including that of the reference genome allele, contain mutations and they thus represent polymorphic pseudogenes that do not produce functional products. These mutations include frameshifting indels, nonsense mutations, and deletions of larger regions. The reference genome haplotype contains a deletion at the 5' end of the gene, including the core promoter region and the transcription start site, and therefore no transcripts result from this haplotype. [provided by RefSeq, Aug 2011]
预测分子量29 kDa
检测图片 (1)
  • ARG21056 anti-MHC Class II antibody [NIMR-4] FACS image

    Flow Cytometry: BALB/c Mouse splenocytes stained with ARG21056 anti-MHC Class II antibody [NIMR-4] followed by Mouse anti-Rat IgG2b antibody (Alexa Fluor® 488).

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