anti-MLLT10 / AF10 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes MLLT10 / AF10
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 特异性: This antibody is expected to recognize both reported isoforms (NP_004632.1; NP_001009569.1).
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: MLLT10 / AF10
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG43682
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整,请以品牌方官网实时更新的价格为准,以确保准确性。
Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes MLLT10 / AF10
反应物种Hu
应用IHC-P, WB
特异性This antibody is expected to recognize both reported isoforms (NP_004632.1; NP_001009569.1).
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称MLLT10 / AF10
抗原物种Human
抗原Synthetic peptide of Human MLLT10 / AF10.
偶联标记Un-conjugated
Protein Full nameProtein AF-10
別名Protein AF-10; AF10; ALL1-fused gene from chromosome 10 protein; MLLT10 histone lysine methyltransferase DOT1L cofactor
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:100
WB1:500 - 1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量130 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
浓度Batch dependent
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 8028 Human MLLT10

Swiss-port # P55197 Human Protein AF-10

基因名称MLLT10
全名MLLT10 histone lysine methyltransferase DOT1L cofactor
背景介绍This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
生物功能Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302). [UniProt]
细胞定位Nucleus
研究领域Gene Regulation antibody
预测分子量113 kDa
翻译后修饰Isopeptide bond; Phosphoprotein; Ubl conjugation
New Products
Get in touch with AREX
Name:*
Tel/Phone:*
Company:*
Email:*
Inquiry:
Captcha*
Submitting your email information means that you are willing to receive email information from AREX regarding technology, applications, products, and events. By clicking on the 'unsubscribe' button in the email or by contacting info@arexbio.com You can unsubscribe at any time by sending an email. Regarding your data usage information, please refer to our privacy policy.
© AREX 2024. All Rights Reserved. | 浙ICP备2024113709号-3 Sitemap