anti-NCF1 / p47phox antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes NCF1 / p47phox
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: NCF1 / p47phox
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human NCF1 (NP_000256.4)
  • Brand:
CAT.NO. : ARG55464
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes NCF1 / p47phox
反应物种Hu, Ms, Rat
应用ICC/IF, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称NCF1 / p47phox
抗原物种Human
抗原Recombinant protein of Human NCF1 (NP_000256.4)
偶联标记Un-conjugated
別名Nox organizer 2; SH3PXD1A; NCF-47K; 47 kDa autosomal chronic granulomatous disease protein; NOXO2; Nox-organizing protein 2; 47 kDa neutrophil oxidase factor; Neutrophil cytosol factor 1; SH3 and PX domain-containing protein 1A; p47phox; NCF1A; Neutrophil NADPH oxidase factor 1; p47-phox; NCF-1
应用说明
预测反应性说明Rat
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IPAssay-dependent
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Mouse lung
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 17969 Mouse NCF1

GeneID: 653361 Human NCF1

Swiss-port # P14598 Human Neutrophil cytosol factor 1

Swiss-port # Q09014 Mouse Neutrophil cytosol factor 1

基因名称NCF1
全名neutrophil cytosolic factor 1
背景介绍The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
生物功能NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). [UniProt]
研究领域Cancer antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量45 kDa
翻译后修饰Phosphorylated by PRKCD; phosphorylation induces activation of NCF1 and NADPH oxidase activity.
检测图片 (1)
  • ARG55464 anti-NCF1 / p47phox antibody WB image

    Western blot: Mouse lung lysate stained with ARG55464 anti-NCF1 / p47phox antibody.

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