anti-NMI / n Myc Interactor antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG59185
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes NMI / n Myc Interactor |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1580CT730.43.59 |
| 同位型 | IgG1, kappa |
| 靶点名称 | NMI / n Myc Interactor |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human NMI. |
| 偶联标记 | Un-conjugated |
| 別名 | N-myc and STAT interactor; N-myc-interactor; Nmi |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A431 | ||||
| 实际分子量 | ~ 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NMI |
| 全名 | N-myc (and STAT) interactor |
| 背景介绍 | NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 35 kDa |
检测图片 (1)
ARG59185 anti-NMI / n Myc Interactor antibody WB image
Western blot: 20 µg of A431 cell lysate stained with ARG59185 anti-NMI / n Myc Interactor antibody at 1:2000 dilution.
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