anti-PDE1C antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PDE1C
  • 反应物种: Hu, Ms, Rat
  • 应用: Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PDE1C
  • 抗原物种: Human
  • 抗原: Synthetic peptide from Human PDE1C.
  • Brand:
CAT.NO. : ARG10793
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PDE1C
反应物种Hu, Ms, Rat
应用Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PDE1C
抗原物种Human
抗原Synthetic peptide from Human PDE1C.
偶联标记Un-conjugated
別名Hcam3; cam-PDE 1C; EC 3.1.4.17; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; hCam-3
应用说明
应用建议
应用推荐稀释比
Confocal1:40 - 1:100
Dot1:10000
ELISA1:10000
ICC/IF1:40 - 1:100
IHC-P1:40 - 1:100
IP1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA.
抗菌剂0.02% Sodium azide
稳定剂30% Glycerol and 0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 18575 Mouse PDE1C

GeneID: 5137 Human PDE1C

GeneID: 81742 Rat PDE1C

基因名称PDE1C
全名phosphodiesterase 1C, calmodulin-dependent 70kDa
背景介绍Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009]
生物功能Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. [UniProt]
预测分子量PDE1C1: 76 kDa
PDE1C2: 70 kDa
检测图片 (3)
  • ARG10793 anti-PDE1C antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10793 anti-PDE1C antibody at 1:1500 dilution.

  • ARG10793 anti-PDE1C antibody WB image

    Western blot: Recombinant PDE1C2 and PDE1C1 protein stained with ARG10793 anti-PDE1C antibody at 1:500 dilution.

  • ARG10793 anti-PDE1C antibody WB image

    Western blot: 50 µg of Rat brain on SDS-PAGE stained with ARG10793 anti-PDE1C antibody at 1:250 dilution.

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