anti-PLOD1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PLOD1
  • 反应物种: Hu
  • 预测物种: Ms
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PLOD1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG55680
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PLOD1
反应物种Hu
预测物种Ms
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PLOD1
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 66-94 (N-terminus) of Human PLOD1.
偶联标记Un-conjugated
別名EC 1.14.11.4; EDS6; Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; Lysyl hydroxylase 1; LH; PLOD; LLH; LH1
应用说明
应用建议
应用推荐稀释比
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照A431
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide.
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5351 Human PLOD1

Swiss-port # Q02809 Human Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

基因名称PLOD1
全名procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
背景介绍Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]
生物功能Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. [UniProt]
细胞定位Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side
预测分子量84 kDa
检测图片 (1)
  • ARG55680 anti-PLOD1 antibody WB image

    Western blot: 20 µg of A431 cell lysate stained with ARG55680 anti-PLOD1 antibody at 1:1000 dilution.

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