anti-PMVK antibody [21C10]
![anti-PMVK antibody [21C10]](/upload/image/products/ARG57043_WB_1_210_205.jpg)
![anti-PMVK antibody [21C10]](/upload/image/products/ARG57043_FACS_1.jpg)
![anti-PMVK antibody [21C10]](/upload/image/products/ARG57043_WB_1.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57043
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [21C10] recognizes PMVK |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 21C10 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | PMVK |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-192 of Human PMVK. |
| 偶联标记 | Un-conjugated |
| 別名 | PMKase; PMKASE; hPMK; PMKA; HUMPMKI; EC 2.7.4.2; Phosphomevalonate kinase; PMK |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PMVK |
| 全名 | phosphomevalonate kinase |
| 背景介绍 | This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011] |
| 预测分子量 | 22 kDa |
检测图片 (2)
ARG57043 anti-PMVK antibody [21C10] FACS image
Flow Cytometry: LNCap cell line stained with ARG57043 anti-PMVK antibody [21C10] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
ARG57043 anti-PMVK antibody [21C10] WB image
Western blot: 40 µg of 1) HeLa cell lysate, 2) HepG2 cell lysate, 3) Jukat cell lysate, 4) MCF7 cell lysate, 5) A549 cell lysate stained with ARG57043 anti-PMVK antibody [21C10] at 1:1000.
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