anti-Retinoid X Receptor gamma antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Retinoid X Receptor gamma
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Retinoid X Receptor gamma
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 1-137 of Human Retinoid X Receptor gamma (NP_008848.1).
  • Brand:
CAT.NO. : ARG41053
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Retinoid X Receptor gamma
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Retinoid X Receptor gamma
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 1-137 of Human Retinoid X Receptor gamma (NP_008848.1).
偶联标记Un-conjugated
別名NR2B3; Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma; Retinoic acid receptor RXR-gamma; RXRC
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:100
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Jurkat
实际分子量60 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20183 Mouse RXRG

GeneID: 6258 Human RXRG

GeneID: 83574 Rat RXRG

基因名称RXRG
全名retinoid X receptor, gamma
背景介绍This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
生物功能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). [UniProt]
细胞定位Nucleus. [UniProt]
预测分子量51 kDa
检测图片 (2)
  • ARG41053 anti-Retinoid X Receptor gamma antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Mouse testis stained with ARG41053 anti-Retinoid X Receptor gamma antibody at 1:100 dilution.

  • ARG41053 anti-Retinoid X Receptor gamma antibody WB image

    Western blot: 25 µg of Jurkat cell lysate stained with ARG41053 anti-Retinoid X Receptor gamma antibody at 1:1000 dilution.

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