anti-Tissue Factor antibody [TF9-10H10]

产品描述: Mouse Monoclonal antibody [TF9-10H10] recognizes Tissue FactorMouse anti Human CD142 antibody, clone TF9-10H10 recognizes human CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Mouse anti Human CD142 antibody, clone TF9-10H10 recognizes an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.
反应物种: Hu, NHuPrm
不反应物种: Rb
应用: FACS, ICC/IF, IHC-Fr, WB
宿主: Mouse
克隆: Monoclonal
克隆号: TF9-10H10
同位型: IgG1
靶点名称: Tissue Factor

CAT.NO. : ARG23394

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [TF9-10H10] recognizes Tissue Factor Mouse anti Human CD142 antibody, clone TF9-10H10 recognizes human CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation.Mouse anti Human CD142 antibody, clone TF9-10H10 recognizes an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.
反应物种	Hu, NHuPrm
不反应物种	Rb
应用	FACS, ICC/IF, IHC-Fr, WB
宿主	Mouse
克隆	Monoclonal
克隆号	TF9-10H10
同位型	IgG1
靶点名称	Tissue Factor
抗原物种	Human
抗原	Denatured Tissue factor isolated from human brain by the Factor VII affinity method (Guha et al. 1986).
偶联标记	Un-conjugated
別名	Thromboplastin; Tissue factor; TFA; CD142; TF; Coagulation factor III; CD antigen CD142

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS, 0.09% Sodium azide and 200 mM Mannitol.
抗菌剂	0.09% Sodium azide
稳定剂	200 mM Mannitol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 2152 Human F3 Swiss-port # P13726 Human Tissue factor
基因名称	F3
全名	coagulation factor III (thromboplastin, tissue factor)
背景介绍	This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
生物功能	Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. [UniProt]
预测分子量	33 kDa (unmodified); 45-50 kDa (glycosylated)

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