BRM Rabbit Monoclonal Antibody(ARA929)
Key features and details
- Reactivity:Human, Monkey
- Application:IHC
- Host:Rabbit
- Clonality:Monoclonal
- Target:BRM
-
Brand:
CAT.NO. : ARA6766
RMB Please choose
RMB Please choose
Product Details
Background
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene. The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
Application
|
Application |
Dilution Ratio |
|
IHC-P |
1:50-1:200 |
Overview
|
Antibody Type |
Recombinant Rabbit monoclonal Antibody |
|
Immunogen |
Synthetic peptide within human SMARCA2 aa 231-280 / 1,590 |
|
Species Reactivity |
Human, Monkey |
|
Validated Applications |
WB, IHC-P, FC |
|
Molecular Weight |
Predicted band size: 181 kDa |
|
Positive Control |
HeLa cell lysate, HepG2 cell lysate, A549 cell lysate, MCF7 cell lysate, COS-1 cell lysate, human colon carcinoma tissue, human prostate carcinoma tissue, MCF7 |
|
Conjugation |
unconjugated |
|
Form |
Liquid |
|
Concentration |
1μg/μl |
|
Storage Buffer |
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide |
|
Isotype |
IgG |
|
Purification Method |
Protein A affinity purified |
Data
Immunohistochemical staining of human colon carcinoma tissue using BRM Rabbit Monoclonal Antibody(ARA929)
Immunohistochemical staining of human prostate carcinoma tissue using BRM Rabbit Monoclonal Antibody(ARA929)
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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