Human CD121a / IL1 Receptor1 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG81412
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG81412-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81412-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG81412-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81412-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81412-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81412-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81412-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81412-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81412-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81412-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81412-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG81412 Human CD121a / IL1 Receptor1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL1 Receptor I in serum and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | CD121a / IL1 Receptor1 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 62.5 pg/ml |
| 样品类型 | Serum and cell culture supernatants. |
| 标准范围 | 125 - 8000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 5.0% Inter-Assay CV: 6.2% |
| 別名 | Interleukin-1 receptor alpha; sIL-1R1; p80; CD121A; mIL-1RI; IL1R; P80; Interleukin-1 receptor type I; IL1RA; D2S1473; Interleukin-1 receptor type 1; IL-1R-alpha; IL-1RT-1; CD121 antigen-like family member A; IL-1R-1; sIL-1RI; IL-1RT1; mIL-1R1; CD antigen CD121a |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL1R1 |
| 全名 | interleukin 1 receptor, type I |
| 背景介绍 | This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013] |
| 生物功能 | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. [UniProt] |
| 产品亮点 | Related products: IL1 Receptor antibodies; IL1 Receptor ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | A soluble form (sIL1R1) is probably produced by proteolytic cleavage at the cell surface (shedding). Rapidly phosphorylated on Tyr-496 in response to IL-1, which creates a SH2 binding site for the PI 3-kinase regulatory subunit PIK3R1. [UniProt] |
检测图片 (1)
ARG81412 Human IL1 Receptor I ELISA Kit standard curve image
ARG81412 Human IL1 Receptor I ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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