Mouse C1q / Complement 1q ELISA Kit
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- 反应物种:
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- 偶联标记:
- 偶联标记说明:
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CAT.NO. : ARG83485
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Product Details
概述
| 产品描述 | ARG83485 Mouse C1q / Complement 1q ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse C1q / Complement 1q in Plasma, Serum |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 靶点名称 | C1q / Complement 1q |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 1.5 ng/ml |
| 样品类型 | Plasma, Serum |
| 标准范围 | 3.125 - 200 ng/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | C1QA; Complement C1q A Chain; Complement Component 1, Q Subcomponent, Alpha Polypeptide; Complement Component 1, Q Subcomponent, A Chain; Complement C1q Subcomponent Subunit A; Complement C1q Chain A; Complement Component C1q, A Chain; C1QD1 |
应用说明
| 检测时间 | 2 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P98086 Mouse Complement C1q subcomponent subunit A |
|---|---|
| 基因名称 | C1QA |
| 全名 | complement component 1, q subcomponent, A chain |
| 背景介绍 | This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. |
| 生物功能 | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Hydroxylation |
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