Recombinant Human/Murine Fibroblast Growth Factor-8b

Key features and details

Species: Human
Abbreviation: rHu/MuFGF-8b
Source: Expressed in E. coli.
Molecular Weight: Approximately 22.5 kDa, a single non-glycosylated polypeptide chain containing 194 amino acids.
Purity: ＞97% by SDS-PAGE or HPLC.
Endotoxin: < 0.01 EU/μg of rHu/MuFGF-8b protein as determined by LAL method.
Accession #: P55075-3 Gln23-Arg215 with an N-terminal Met
Storage:

Brand:

CAT.NO. : ARP6658

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Size:

50μg

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Product Details

Background

FGF-8 (FGF-8b) is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8 (FGF-8A, 8B, 8E and 8F) . The human and murine FGF-8A and B are identical, unlike human and mouse FGF-8E and F, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant Human/Murine FGF-8 (FGF-8b) is a 22.5kDa protein consisting of 194 amino acid residues.

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